Danny x a man from a meme very cursed

2021.11.30 10:11 thoughtsonyt Danny x a man from a meme very cursed

Danny x a man from a meme very cursed submitted by thoughtsonyt to DannyGonzalez [link] [comments]


2021.11.30 10:11 Chervi_UwU Where update (No offence to any developers I know it isn't their fault)

submitted by Chervi_UwU to PixelGun [link] [comments]


2021.11.30 10:11 WheelassassinYT Banana??

Banana?? submitted by WheelassassinYT to Minecraft [link] [comments]


2021.11.30 10:11 Ricosss [Effect of Ketone Body β-Hydroxybutyrate to Attenuate Inflammation-Induced Mitochondrial Oxidative Stress in Vascular Endothelial Cells]. (Pub Date: 2021-11)

https://doi.org/10.12182/20211160202
https://pubmed.ncbi.nlm.nih.gov/34841761
Abstract Objective
To investigate the regulatory function and mechanism of β-hydroxybutyrate (β-OHB), a ketone body, on the mitochondrial oxidative stress of inflammatory human umbilical vein endothelial cells (HUVECs).
Methods
Lipopolysaccharide (LPS) and adenosine triphosphate (ATP) were used to induce macrophages to release proinflammatory factors, and the culture supernatant was collected as a macrophage-conditioned medium (MCM) to culture HUVECs. A total of 7 groups of cells were used in the study: ①control group, or normal cultured HUVECs, ②MCM group, or the MCM-cultured HUVECs, groups ③ to ⑦ were all HUVECs co-cultured with different reagents, including ③MCM β-OHB group, ④MCM N-acetylcysteine (NAC) group, ⑤MCM β-OHB NAC group, ⑥MCM β-OHB histone deacetylase agonist ITSA1 group, and ⑦MCM β-OHB histone deacetylase inhibitor Entinostat group. MitoSOX immunofluorescence staining was conducted to analyzes the mitochondrial superoxide levels, real-time fluorescent quantitative polymerase chain reaction (RT-qPCR) was performed to examine the mRNA expression of antioxidant genes, and Seahorse mitochondrial energy analyzer was used to measure mitochondrial aerobic respiration capacity.
Results
Compared with the control group, mitochondrial superoxide production was significantly increased in the MCM cultured HUVECs cells, while β-OHB treatment significantly inhibited mitochondrial superoxide production, which was accompanied by an increase in the mRNA expression of antioxidant genes, and significant increase in the basal mitochondrial oxygen consumption rate and respiratory reserve capacity. NAC treatment did not further enhance the protective effect of β-OHB on mitochondrial functions. In addition, ITSA1 treatment could completely offset the antioxidant and mitochondrial protective effects of β-OHB, and these stated effects were still maintained after Entinostat treatment.
Conclusion
The ketone body β-OHB attenuates the mitochondrial oxidative stress of vascular endothelial cells through activating the antioxidant pathway and inhibiting histone deacetylase activity.
submitted by Ricosss to ketoscience [link] [comments]


2021.11.30 10:11 eastern_eu_baby Hey there ❤️

Hey there ❤️ submitted by eastern_eu_baby to FreckledGirls [link] [comments]


2021.11.30 10:11 Hotelsarah1234 [Thanks] Tinawebmom 😃😃😃 you Christmased me right up!!! Thank you!!! 🎅🎅🎅

[Thanks] Tinawebmom 😃😃😃 you Christmased me right up!!! Thank you!!! 🎅🎅🎅 submitted by Hotelsarah1234 to Random_Acts_Of_Amazon [link] [comments]


2021.11.30 10:11 Good-Plane-1020 Just Fair-launched!🚀 A Tidal Wave 🌊 of Profits to 🔱Aqua Shiba's investors! Join the Heroic Aqua Shiba on his heroic crusade to save the Crypto & Defi World! Join our Royal Atlantian Army as we embark on our campaign to build the most heroic community to save Crypto and DeFi!

Just Fair-launched!🚀 A Tidal Wave 🌊 of Profits to 🔱Aqua Shiba's investors! Join the Heroic Aqua Shiba on his heroic crusade to save the Crypto & Defi World! Join our Royal Atlantian Army as we embark on our campaign to become the #1 DeFi Token in all of Crypto. Join 🔱Aqua Shiba Today. Lend us your strength!
🔱Aqua Shiba just Launched🚀 from depths of the Majestic Ocean and bringing a Tidal Wave 🌊 of Profits to his investors! Join the Royal Atlantian Army!
🌐Website: https://www.aquashiba.cc
📱Telegram: https://t.me/AquaShibaCoin
🐤Twitter: https://twitter.com/AquaShibaCoin
🌐BSC Scan: https://bscscan.com/token/0x37B8996C92f9143aE82183280b120a3499Ab0b3C
Liquidity is locked: https://deeplock.io/lock/0xabAF6f50Ac9219B9E19e35D97773294Aa6141e10
Contract Ownership is Renounced: https://bscscan.com/tx/0xb7604d35e9873e076060b4f87d6ce70df13e039e84fd0106a0e227d95ad0187a
📝Contract: 0x37B8996C92f9143aE82183280b120a3499Ab0b3C
Buy with 11% Slippage right here on PancakeSwap!
Aqua Shiba has assembled his greatest generals to form the Royal Atlantian Marketing Council to market our token far and wide by advertising via multiple avenues such as Reddit, Twitter, Facebook, Token Listing sites, and much more.
The Bounties of Aqua Shiba's Heroic Campaign will be shared with all his loyal hodlers via Heroic Reflection Rewards, Token Airdrops and Community Awards and Prizes.
Our Tokenomics are as follows:
Auto-Liquidity: All Aqua Shiba transactions contribute 7% to our liquidity pool ensuring price stability, sustainable growth for all his Aqua Shiba investors. Multiple liquidity pools and stable coins parings with BUSD & USDC will be added as our community grows.
Safe & Secure: Aqua Shiba puts the safety and security of his Army as his top priority and has ordered that Contract Ownership be Renounced at launch & 100% of Liquidity be Locked, therefore, ensuring that his token is decentralized and no individual, group, or entity has control over his royal token and ensuring safety and security for all his investors.
Heroic Reflections: All Aqua Shiba holders will observe their token balance grow through Reflection Rewards at intervals as the community grows. This function will allow holders to effectively earn interest over time and will scale as the community grows.
Heroic Marketing: Aqua Shiba has formed the Royal Atlantian Marketing Council which will utilize the Royal Atlantian Treasury of which 3% of every transaction is contributed to launch a Marketing Campaign covering multiple avenues such as Reddit, Twitter, Facebook, Token Listing sites, and much more. Aqua Shiba is going to save the entire crypto world and rain riches down on his loyal soldiers!
submitted by Good-Plane-1020 to ico [link] [comments]


2021.11.30 10:11 MylesTheFox99 When do you find it best to use music, ambient sounds, or just have no background noise?

I’ve been DMing for a respectable amount of time now (~2 years). I’ve got down how to run and plan a game, so I’ve started to think about how I could further enhance the experience of my players.
I already use music in my campaigns, but I started wondering if there are times when it would be better to use only ambient sounds or just have total silence.
What do you guys think? What works for you? What combination of those three things do you and your players get the most out of?
submitted by MylesTheFox99 to DMAcademy [link] [comments]


2021.11.30 10:11 Wise-Elk-3468 The Omicron Variant is sending me over the edge

I'm scared that it might evade the existing vaccines and put us into lockdown again.
submitted by Wise-Elk-3468 to Pandemic [link] [comments]


2021.11.30 10:11 MikeTheDude23 E.A after seeing Farming Sims beating Battlefield:

E.A after seeing Farming Sims beating Battlefield: submitted by MikeTheDude23 to battlefield2042 [link] [comments]


2021.11.30 10:11 Solfaroiy ⚔️ AlienX ⚔️ a Fantasy Anime Style PVP Play-To-Earn NFT game ⚡ Launching Now on BSC ❤ Low Marketcap!! ☀︎ Join our telegram!



Welcome To ⚔️ AlienX ⚔️
⚔️ a Fantasy Anime Style PVP Play-To-Earn NFT game ⚔️
⚡️Explore the world of Zaidara through a thrilling campaign mode, or battle PVP and reap the rewards⚡️
Contract Address: 0x0B34c221fb0e8E1C20a51dC894f8d3EF63aee18c
‍♀️ Fully Doxxed Team
☄︎ Earn Rewards in BUSD
☘︎ 2 Full Audits Done (dessert finance & Techrate)
☝︎ 100% Transparency
☠︎ V2 contract LAUNCHED on PCS! ☠︎
➡️ NY billboards, celebrities and much more in the next few days.
⛩️ Tokenomics
✈️3% Marketing Fee
✈1% Charity Donation
✈️2% Buy Back Fee
✈️3% Liquidity Premium
✈️7% BUSD Reflections
❄️Liquidity Lock 1 year
♟️ Token Details ♟️
Contract Address: 0x0B34c221fb0e8E1C20a51dC894f8d3EF63aee18c
Liquidity: https://deeplock.io/lock/0x95817268b301Bd83566D4aC5132Ad693662a14e2
Name: AlienX
Symbol: ALX
Decimals: 9
☢️ Useful Links
↪️ Pancakeswap: https://pancakeswap.finance/swap?outputCurrency=0x0B34c221fb0e8E1C20a51dC894f8d3EF63aee18c
↪️ Website: https://alienx.online/
↪️ Telegram: https://t.me/AlienxOnline
↪️ Twitter: https://twitter.com/AlienXOffical
submitted by Solfaroiy to CryptoMoonCoins [link] [comments]


2021.11.30 10:11 TypicalLondonOtaku Hari - Born by the river Insta post!

submitted by TypicalLondonOtaku to coversongs [link] [comments]


2021.11.30 10:11 nezbla Recommendations for a barber / hairdresser for a fella with long hair to get it trimmed / tidied up a bit.

Yeah bit of an odd one, I've wanted to grow my hair out for decades but there was always SOMETHING that meant I had to have it cut short and smart, job interview, wedding... Whatever.
Well, lockdown provideth... (not sure I'd count it as a positive without sounding like a twat, but ya know what I mean).
Thing is, I'm used to going to a barbers and getting a, very standard "short back and sides".
I've never in my life gone to a "salon" or anything.
I just need it tidied up a little bit, but I'm not sure your average £10 barber is the right place...
I may well be overthinking it.
Any advice for somewhere in Brighton?
submitted by nezbla to brighton [link] [comments]


2021.11.30 10:11 ZmanB-Bills TRUTH. Great article, depicting FACTS that ALL come straight from a Senate Select Committee led by a Republican (Burr) in a Republican controlled Senate. Interesting read for all you "Truth" seekers.

TRUTH. Great article, depicting FACTS that ALL come straight from a Senate Select Committee led by a Republican (Burr) in a Republican controlled Senate. Interesting read for all you submitted by ZmanB-Bills to DWAC [link] [comments]


2021.11.30 10:11 mylefttoeiscold Sainsbury

Sainsbury submitted by mylefttoeiscold to ihadastroke [link] [comments]


2021.11.30 10:11 UnluckyChemist2162 Company demanded I give one month instead of two weeks notice. I'm now going to do the bare minimum

Work for a horrible Fortune 500 company as an analyst, I know that I'm blessed to work a white collar job. But the company is one of the worst in the industry, treats people like crap, won't give promotions, underpays everyone, hassles them about overtime and expects them to do more during their regular hours....
They demanded that I give them at least a month notice, so work an entire month here instead of the standard two weeks. Outrageous, really. So in response, I fully intend on doing the bare minimum over the next two weeks. Literally, the exact same everyone else on the team has been doing the entire time I've been here going above and beyond with no reward.
I mean, what are they going to do, fire me? HAHAHA
submitted by UnluckyChemist2162 to antiwork [link] [comments]


2021.11.30 10:11 AnnamariaHarvison Got these exothermic reusable heat packs at the gun show. Fun to watch activating and get up to 130 degrees, so its hot!! Awesome , highly recommend.

Got these exothermic reusable heat packs at the gun show. Fun to watch activating and get up to 130 degrees, so its hot!! Awesome , highly recommend. submitted by AnnamariaHarvison to Damnthatsinteresting [link] [comments]


2021.11.30 10:11 GodOfBongs420 As my hometown Mumbai gears up for 2nd Test, here's a dusky vibe of Wankhede and Brabourne Stadium situated at the sea shore

As my hometown Mumbai gears up for 2nd Test, here's a dusky vibe of Wankhede and Brabourne Stadium situated at the sea shore submitted by GodOfBongs420 to Cricket [link] [comments]


2021.11.30 10:11 SellHealthy2688 Could you guys help me out with a F2P Royal Giant deck. I’m not F2P but I’m struggling to upgrade my deck fast. Here are some of my high level cards.

Could you guys help me out with a F2P Royal Giant deck. I’m not F2P but I’m struggling to upgrade my deck fast. Here are some of my high level cards. submitted by SellHealthy2688 to ClashRoyale [link] [comments]


2021.11.30 10:11 LezardVariath Welcome to the Lake! 21+ SFW Server! We are a very chill (and wholesomely toxic) community hoping to find new long lasting friends. Come talk life, anime, games, you name it! [Not a Dating Server]

Welcome to the Lake! 21+ SFW Server! We are a very chill (and wholesomely toxic) community hoping to find new long lasting friends. Come talk life, anime, games, you name it! [Not a Dating Server] submitted by LezardVariath to DiscordAdvertising [link] [comments]


2021.11.30 10:11 Present-Call-3781 MungyFinance | Launching Now! | Experienced devs | Locked liquidity | Great tokenomics! |

MungyFinance | Launching Now! | Experienced devs | Locked liquidity | Great tokenomics! | MungyFinance | Launching Now! | Experienced devs | Locked liquidity | Great tokenomics! |
https://preview.redd.it/uigujybrfq281.jpg?width=686&format=pjpg&auto=webp&s=79ec9236645e307f338d72308c98de7ebb4733af
Hi there guys ! Today I will be bringing attention to a brand new project that I have come acrross! It is called MungyFinance and for me it ticks all the boxes and things I look for when researching and investing into a new project!

An overview of MungyFinance :

🔐 Locked Liquidity,

✅ Verified Contract, our contract is verified, this means anyone can take a read through it when they please.

🐳 Anti-Whale System, we have a anti-whale system, so only a maximum of 10T can be made per transaction.

🏪 Marketing Wallet and Charity Wallet, we will have a marketing wallet and charity wallet, this wallet will gain 2 percent each per transaction that is taken place.

MungyFinance Tokenomics

MungyFinance is a hyper-deflationary token, all holders will be rewarded for holding tokens via static reflection.

So what exactly happens every time a transaction takes place? 4 percent will be sent over to our liquidity pool, growing our liquidity so that our lowest floor point will constantly keep rising. A further 4 percent is then equally split amongst all holders depending on how many tokens are being held by them.

Then a further 4 percent will go into the marketing and Charity Wallet (2% to each wallet, which will be used to market this token and the development of our application). We will also be having a anti-whale system in place so a maximum transaction of 10T tokens can only take place at a time!

MungyFinance Distribution ♻️

Total Tokens:

1,000,000,000,000(100%)

Locked Tokens:

500,000,000,000 (50%)

PancakeSwap Tokens:

480,000,000,000 (48%)

Developer Tokens:

20,000,000,000 (2%)

MungyFinance Links:

Telegram✈️ https://t.me/MungyFinance


🥞 PancakeSwap (V2):
https://exchange.pancakeswap.finance/#/swap?outputCurrency=0xF144a91D711cDd1324AeE1c13E19b1b0fF2dDD2D



📈 Chart (Bogged): https://charts.bogged.finance/?token=0xF144a91D711cDd1324AeE1c13E19b1b0fF2dDD2D
submitted by Present-Call-3781 to Moonshotcoins [link] [comments]


2021.11.30 10:11 patricia_mol Any active and single sugar baby here ?

submitted by patricia_mol to SugarMommyClub [link] [comments]


2021.11.30 10:11 D4rk_Z3kr0m Cresselia on me 4136 5615 931a

Raid
submitted by D4rk_Z3kr0m to PokemonGoFriends [link] [comments]


2021.11.30 10:11 TheLaw433 Help needed with opencore!

Help needed with opencore! submitted by TheLaw433 to hackintosh [link] [comments]


2021.11.30 10:11 PasaKala People in 1981

People in 1981 submitted by PasaKala to dankmemes [link] [comments]


http://snegir-t.ru